A Cross-Sectional Analysis of Registered Studies on the Promising Dipeptide Carnosine

Abstract Carnosine (β-Alanyl-L-Histidine) is a naturally occurring endogenous dipeptide and over-the-counter dietary supplement with multimodal mechanism of action. The use carnosine its analogues in as diverse mode action application. Carnosine’s ready availability protective properties make it an interesting candidate for clinical use. We have now examined the registered studies. In cross-sectional study, we evaluated status studies on analogues. searched all 16 primary trials registries listed WHO Clinical Trials Registry. Registered to published were identified ratio published/unpublished well time publication thematic focus evaluated. selected 70 carnosine, which 34 been completed 25 date, average 28 months. Carnosine/carnosine used supplements 56% Twelve healthy volunteers that focused changes underlying physiology. other 22 deal various pictures, particular metabolic psychological disorders. This structured evaluation shows applications are very versatile, registration one timely would facilitate planning further